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America's Most-Searched Skincare Ingredients, Ranked

America's Most-Searched Skincare Ingredients, Ranked
Okoaskin Dual Action Lifting Cream
#1 Most-Searched: Peptides

Okoaskin Dual Action Lifting Cream

The ingredient America searches for most

Peptides: the most-searched skincare ingredient in the US, and Okoaskin's hero active. IDEALIFT (acetyl dipeptide-1 cetyl ester) is the peptide in the Okoaskin Dual Action Lifting Cream.

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What changed
  • Re-pulled both datasets on August 27, 2026: national volume for 13 ingredients and the five-serum state map.
  • Updated the rankings to the trailing twelve months, where peptides lead on 49,500 average monthly searches.
  • Added the peak-versus-now table showing peptides down 63% off their April high while retinol and niacinamide sit at twelve-month highs.
  • Rebuilt the state map from a single comparative query, which now shows vitamin C serum leading in all 51 jurisdictions.

Okoaskin analyzed over five years of Google search data to determine which skincare ingredients Americans search for most, and how dramatically the landscape has shifted since 2020.

Data pulled: August 27, 2026. Okoaskin updates this page as new data periods become available.

State scores reflect the most recent 12-month period. National volume data reflects 2020-early 2026.

Peptides now dominate American skincare interest by a wide margin nationally - and at the state level, peptide serum has overtaken retinol serum to lead in 18 states, up from 11 in Okoaskin's previous data pull.

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  • Peptides is still the most-searched skincare ingredient in the US, averaging 49,500 searches a month over August 2025 to July 2026, more than the other nine tracked ingredients combined (34,600).
  • Peptides peaked and are falling. Search volume hit 110,000 in April 2026 and stood at 40,500 in July, 63% off the peak.
  • Retinol and niacinamide both hit twelve-month highs in July 2026, at 9,900 and 3,600 searches. Retinol interest is rising, not fading.
  • Vitamin C serum leads every state. In a comparative pull of five serum terms across all 50 states and DC, vitamin C serum scored highest in all 51, ranging from 25 to 42 out of 100.
  • Three ingredients dropped out of the rankings entirely. Tretinoin, bakuchiol and copper peptides no longer clear the reporting threshold.

The Full Rankings

Okoaskin tracked monthly Google search volume for [ingredient] skincare queries over August 2025 to July 2026. Ten ingredients cleared the reporting threshold in this pull; tretinoin, bakuchiol and copper peptides fell below it and are no longer listed.

Okoaskin Dual Action Lifting Cream #1 Most-Searched · Okoaskin Okoaskin Dual Action Lifting Cream - built on IDEALIFT (acetyl dipeptide-1 cetyl ester), from the peptide class that tops this ranking, number one by a wide margin. IDEALIFT is the peptide in the Okoaskin Dual Action Lifting Cream. $44.88 Subscribe & Save $61.90 · Save 28% Shop the Lifting Cream
Rank Ingredient Avg. monthly searches
1 Peptides 49,500
2 Hyaluronic acid 14,800
3 Retinol 5,400
4 Vitamin C 3,600
5 Snail mucin 2,900
6 Niacinamide 2,400
7 Salicylic acid 1,900
8 Collagen 1,300
9 Sunscreen 1,300
10 Azelaic acid 1,000

Where Each Ingredient Peaked and Where It Sits Now

The headline number in the ranking above is a twelve-month average, which hides the shape of the year. This table shows the month each ingredient peaked, the peak volume, and July 2026 against it.

Ingredient Peak month Peak volume July 2026 Off peak
Peptides Apr 2026 110,000 40,500 -63%
Hyaluronic acid Apr 2026 33,100 5,400 -84%
Retinol Jul 2026 9,900 9,900 At 12-month high
Vitamin C Jun 2026 5,400 2,900 -46%
Snail mucin Jan 2026 5,400 2,400 -56%
Niacinamide Jul 2026 3,600 3,600 At 12-month high
Salicylic acid Jan 2026 2,900 1,300 -55%
Collagen Feb 2026 1,900 1,000 -47%
Sunscreen Mar 2026 1,900 1,300 -32%
Azelaic acid Jun 2026 1,300 1,000 -23%

The Longer View: 2020 to 2026

This table is the series as pulled on April 13, 2026. Years 2020 to 2025 are unchanged by the August re-pull.

Ingredient 2020 2021 2022 2023 2024 2025 2026*
Peptides 172 192 2,870 10,300 12,400 19,442 82,250
Hyaluronic acid 2,840 2,283 1,725 1,525 1,883 9,575 18,500
Retinol 3,425 2,875 3,033 2,992 2,733 4,183 5,500
Snail mucin 82 86 247 972 785 2,457 4,150
Vitamin C 2,700 2,842 3,250 3,617 3,775 3,742 4,000
Niacinamide 1,750 1,858 1,174 646 760 2,292 3,250
Salicylic acid 546 509 572 701 870 1,955 2,400
Collagen 638 1,150 895 1,010 1,600 1,300 1,900
Sunscreen 430 568 562 486 853 1,375 1,450
Azelaic acid 434 256 217 276 485 833 1,300
Tretinoin 278 371 491 856 1,358 644 940
Bakuchiol - - 194 216 318 682 860
Copper peptides - 84 147 102 126 338 720

*The 2026 column in this table is a January-February average from the April 13, 2026 pull and has since been superseded: peptides peaked at 110,000 in April and stood at 40,500 in July. The rankings at the top of this page carry the current figures. Years 2020 to 2025 are unchanged.

A correction to the April 2026 state findings

The April version of this page reported that peptide serum led in 18 states, retinol serum in 14 and niacinamide serum in 12. That finding does not survive a like-for-like re-pull, and Okoaskin is retracting it.

The error was in how the five maps were compared. Google Trends normalizes each keyword to its own 0-to-100 scale, so every term has some state scoring 100 regardless of how small the term is. Comparing five separately normalized maps as though they shared a scale inflates whichever term has the least absolute volume. Peptide serum is the smallest of the five at 9,900 searches a month against 135,000 for hyaluronic acid serum, so it was the term that error flattered most.

The table below comes from a single query containing all five terms, which is the method this page describes and the one that makes the columns comparable. On that basis vitamin C serum leads in all 51 jurisdictions. The Wyoming and Hawaii standouts reported in April were artifacts of the same normalization and have been removed.

How Big the Five Serum Terms Actually Are

Relative interest scores say nothing about size. These are absolute monthly search volumes for the same five terms, from the same pull, and they explain why the earlier state map was misleading.

Serum term Avg. monthly searches
Hyaluronic acid serum 135,000
Vitamin C serum 90,500
Niacinamide serum 74,000
Retinol serum 33,100
Peptide serum 9,900

Every State's Skincare Serum Profile

Scores are relative search interest from 0 to 100, population-normalized by Google, with all five terms retrieved in a single comparative query so the columns are directly comparable to each other. The highest score in each row is highlighted.

State Retinol serum HA serum Peptide serum Vitamin C serum Niacinamide serum Leads in that state
Alabama 21 15 16 33 15 Vitamin C serum
Alaska 22 16 18 31 13 Vitamin C serum
Arizona 21 14 16 34 15 Vitamin C serum
Arkansas 21 15 17 32 15 Vitamin C serum
California 20 13 16 35 16 Vitamin C serum
Colorado 20 14 16 35 15 Vitamin C serum
Connecticut 21 13 18 33 15 Vitamin C serum
Delaware 20 13 16 36 15 Vitamin C serum
District of Columbia 22 14 16 32 16 Vitamin C serum
Florida 20 14 16 34 16 Vitamin C serum
Georgia 21 13 14 37 15 Vitamin C serum
Hawaii 22 13 16 33 16 Vitamin C serum
Idaho 21 14 20 31 14 Vitamin C serum
Illinois 21 12 14 39 14 Vitamin C serum
Indiana 22 15 16 30 17 Vitamin C serum
Iowa 21 15 16 32 16 Vitamin C serum
Kansas 19 12 12 42 15 Vitamin C serum
Kentucky 22 14 16 33 15 Vitamin C serum
Louisiana 21 15 16 34 14 Vitamin C serum
Maine 23 13 15 36 13 Vitamin C serum
Maryland 20 14 16 34 16 Vitamin C serum
Massachusetts 20 13 14 39 14 Vitamin C serum
Michigan 20 14 15 36 15 Vitamin C serum
Minnesota 22 14 16 33 15 Vitamin C serum
Mississippi 19 13 17 35 16 Vitamin C serum
Missouri 21 15 18 31 15 Vitamin C serum
Montana 24 14 15 33 14 Vitamin C serum
Nebraska 22 14 16 32 16 Vitamin C serum
Nevada 22 14 17 31 16 Vitamin C serum
New Hampshire 21 16 16 31 16 Vitamin C serum
New Jersey 20 13 15 38 14 Vitamin C serum
New Mexico 20 14 16 35 15 Vitamin C serum
New York 19 13 15 37 16 Vitamin C serum
North Carolina 21 13 15 37 14 Vitamin C serum
North Dakota 20 17 17 32 14 Vitamin C serum
Ohio 21 14 16 34 15 Vitamin C serum
Oklahoma 21 15 17 32 15 Vitamin C serum
Oregon 22 14 17 33 14 Vitamin C serum
Pennsylvania 20 13 15 38 14 Vitamin C serum
Rhode Island 20 14 17 35 14 Vitamin C serum
South Carolina 22 14 16 34 14 Vitamin C serum
South Dakota 23 18 15 30 14 Vitamin C serum
Tennessee 20 14 17 33 16 Vitamin C serum
Texas 21 13 18 32 16 Vitamin C serum
Utah 22 14 18 31 15 Vitamin C serum
Vermont 29 13 14 31 13 Vitamin C serum
Virginia 19 13 14 40 14 Vitamin C serum
Washington 19 13 15 38 15 Vitamin C serum
West Virginia 19 14 17 35 15 Vitamin C serum
Wisconsin 22 14 16 34 14 Vitamin C serum
Wyoming 23 15 17 25 20 Vitamin C serum

Methodology

Data source: Google search volume and interest data via DataForSEO API. DataForSEO accesses Google's data infrastructure using the same methodology as Google Trends.

Update frequency: State-level data is updated as new data periods become available. National volume data is updated as new annual periods become available. The data on this page was last pulled on April 13, 2026.

Ingredient selection: Okoaskin selected 13 ingredients that are commonly discussed in skincare media and consumer education. This is not an exhaustive list. Ingredients such as ceramides, glycolic acid, squalane, and others were not included. The ranking reflects only the ingredients analyzed.

National rankings (13 ingredients): Okoaskin retrieved monthly search volume estimates for 13 [ingredient] skincare keyword pairs (e.g., peptides skincare, retinol skincare) from August 2020 through February 2026.

Adding skincare to each ingredient isolates skincare-specific intent and excludes unrelated queries (e.g., peptides for fitness supplements). All volumes represent estimated US monthly searches.

2026 figures reflect January-February 2026 averages only and may not represent full-year trends.

*Sunscreen is a product category rather than a single ingredient, but was included because sunscreen skincare is a common consumer search term.

State-level analysis (5 ingredients): Okoaskin retrieved relative search interest scores for five product-specific keywords: retinol serum, hyaluronic acid serum, peptide serum, vitamin C serum, niacinamide serum.

Data covers all 50 states and Washington DC for the 12 months ending April 2026. All five keywords use the [ingredient] serum format to ensure a consistent, like-for-like comparison. All five keywords were retrieved in a single query to ensure scores are comparable across ingredients within the same pull.

Scores are population-normalized by Google, ranging from 0 to 100, where 100 represents the highest proportional search interest in any state for that keyword.

Limitations:

  • Search volume data reflects what people search for, not what they buy.
  • Search volume estimates are provided by DataForSEO based on Google data. These are modeled estimates, not exact counts.
  • State-level data uses relative interest scores, not absolute search volumes. Wyoming scoring 100 for peptide serum does not mean Wyoming has more total searches than New York. It means Wyoming residents search at a higher rate per capita. Smaller states may show more volatile scores due to lower absolute search volumes.
  • Not all states returned data for all five ingredients. States with missing data points had insufficient volume for that keyword. A state's #1 ingredient is determined from available data only.
  • The national rankings and state-level analysis use different keyword formats ([ingredient] skincare vs [ingredient] serum) and different metrics (raw volume vs relative interest scores). They should be treated as two separate analyses.
  • The 2026 national data includes only January and February, and may not be representative of the full year.
  • This analysis covers Google search data only and does not include searches on Amazon, TikTok, YouTube, or other platforms.
  • This study shows what Americans search for, not why. Okoaskin did not investigate causal factors behind any trends.

Data availability: The full dataset is published as a spreadsheet with the method, the raw figures and the state-level scores: download the workbook.

Okoaskin Dual Action Lifting Cream

Okoaskin Dual Action Lifting Cream

The peptide behind the #1 search term

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Peptides top this ranking, number one by a wide margin. IDEALIFT (acetyl dipeptide-1 cetyl ester) is the one Okoaskin builds on. In IDEALIFT-maker Sederma's two-month, placebo-controlled study, 80% of participants reported firmer-looking skin (supplier evidence, not independent research).

Skin that has lost firmness along the jaw and neck rather than wrinkled responds to peptides such as IDEALIFT (acetyl dipeptide-1 cetyl ester), which supports the elastin network that keeps skin springy. The Okoaskin Dual Action Lifting Cream is $44.88 on subscription ($61.90 one-time) with a 90-day money-back guarantee.

About this research
Data source Google search data via DataForSEO API
Data pulled August 27, 2026
Written by Ashley Mangtani
Reviewed by Lindi Grace, R&D Cosmetic Chemist
Full dataset Download the raw data
Verify it yourself Search peptides skincare in Google Trends

Okoaskin sells a peptide-based product. Okoaskin ran this analysis on public Google data that anyone can reproduce, and Okoaskin publishes the method and dataset so you can check Okoaskin's work.

Okoaskin Dual Action Lifting Cream Okoaskin Dual Action Lifting Cream · IDEALIFT $44.88 $61.90 Shop now
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